Fig. 2.
TRECs after T-cell–depleted or unmodified (T-cell replete) allogeneic hematopoietic stem cell transplantations.
Circulating TRECs per 106 PBMCs were measured and plotted (y-axis) for patients who received unmodified (▪, solid line) versus T-cell–depleted (○, dashed line) allogeneic HSCTs, as a function of time from transplantation (x-axis). The difference between the 2 curves is significant at P < .01, but analysis by quartiles (not shown) indicated that the differences between the 2 groups diminished beyond 9 months. Note that the lower limit of detection for TRECs was 100 TRECs/106 PBMCs in the assay used.