The effect of HLA identity on TREC recovery after transplantation.

TRECs per 10⁶ PBMCs were measured and plotted (y-axis) for samples from patients who were either HLA genotypically identical with their donor (▪, solid line) or not (○, dashed line), as a function of time from transplantation. The latter group included all who had received related but HLA nonidentical allografts or who had received allografts from any unrelated donor (○, dashed line). On the basis of this dichotomization, there was no difference in TRECs between the 2 groups (P = .79). Note that the lower limit of detection for TRECs was 100 TRECs/10⁶ PBMCs in the assay used.