Fig. 6.
Fig. 6. Meiotic recombinations, haplotype sharing, and differential gene expression in the Scp2 cluster. / The frequency of meiotic recombinations within the Scp2interval was determined in the backcross panel that was used to breed congenic B6.DBAScp2 mice (blue line, left y-axis) and in the BXD recombinant inbred panel (data obtained fromhttp://mickey.utmem.edu/MMfiles/MMlist.html; red line, right y-axis). The region of shared haplotypes of B6 and DBA mice (45 to 47 cM) is indicated by the orange box, whereas distinct haplotypes are shown in blue. Differentially expressed stem cell genes (red arrows) clustered in the polymorphic regions in which recombination was severely suppressed.

Meiotic recombinations, haplotype sharing, and differential gene expression in the Scp2 cluster.

The frequency of meiotic recombinations within the Scp2interval was determined in the backcross panel that was used to breed congenic B6.DBAScp2 mice (blue line, left y-axis) and in the BXD recombinant inbred panel (data obtained fromhttp://mickey.utmem.edu/MMfiles/MMlist.html; red line, right y-axis). The region of shared haplotypes of B6 and DBA mice (45 to 47 cM) is indicated by the orange box, whereas distinct haplotypes are shown in blue. Differentially expressed stem cell genes (red arrows) clustered in the polymorphic regions in which recombination was severely suppressed.

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