Fig. 7.
Ratio of protein band 3 to spectrin+ankyrin in RBC membranes from band 3–deficient and spectrin/ankyrin-deficient patients as a function of cell age.
Ratios of protein band 3:spectrin+ankyrin and those of band 4.1a/4.1b were determined on density-fractionated RBCs. Filled symbols indicate patients; open circles, controls. (A) Band 3 deficiency: patients LR2 (black rectangles), AZ10 (dark gray rectangles), WR2 (light gray rectangles). (B) Spectrin/ankyrin deficiency: patients AZ18 (black triangles), AZ16 (gray triangles).