Fig. 4.
Effect of a caspase inhibitor on growth inhibition by TRAIL.
Ph1-positive cell lines sensitive to TRAIL (Nalm1 and KOPM28) were cultured for 30 hours in the absence or presence of rhsTRAIL (25 and 50 ng/mL, respectively) with or without z-VAD-fmk (20 μM) pretreatment, and the 3H-thymidine uptake was determined for the last 6 hours. Data are represented as the mean ± SD of triplicate samples.
