Fig. 5.
Representative Southern blot analysis of 2 NOD/SCID mice that had received transplants of 2 × 105 infected CB CD34+ cells that had been expanded for 4 weeks.
The BM from 2 primary mice (A and B) was injected into 2 different secondary sublethally irradiated NOD/SCID mice (A and B); the BM cells of those mice were injected into 2 different tertiary recipients (A and B). DNA was extracted from the murine BM at week 8 after transplantation and hybridized with a human chromosome 17–specific α-satellite probe. Human-mouse controls are given as percentage of human DNA.