MIP-1α induces migration of MM cells.

(A) MM1.S, (B) pat MM, (C) H929, (D) INA-6, and (E) OPM2 cell migration was measured using a modified Boyden chamber in the presence or absence of MIP-1α in media containing 0% FBS. MIP-1α (0.5, 5, 50, and 500 ng/mL) was added into the lower chamber, and cells migrated into the lower chamber were enumerated after 5 hours. Results were expressed in fold migration relative to control. These results are representative of 3 independent experiments.