Fig. 3.
Recipients of GFP-Tg MIP-1α−/− spleen cells exhibit increased migration into the lung, BALT, and spleen on day 3 after BMT.
Lethally irradiated B10.BR (allogeneic) or C57BL/6 (syngeneic) mice received C57BL/6 BM and either GFP-Tg MIP-1α+/+ or GFP-Tg MIP-1α−/− spleen cells. Shown are in vivo images (1.9-second exposures) of lung, BALT, and spleen captured at day 1 (Figure 3A) and day 3 (Figure 3B) after BMT with a color camera mounted on a stereomicroscope with a GFP filter (× 10.0 zoom factor and × 0.63 transfer lens). “Control” indicates recipient mice receiving allogeneic BM only; images are similar to those of mice receiving syngeneic BM only. Tissues from 1 mouse (of 3 mice) per group per time point are shown.