Fig. 3.
The effects of VEGF and sNRP-1 supplementation on chloroma growth in vivo.
(A) Tumor volume curves. M1 cells (2 × 106 per mouse) were injected subcutaneously into SCID mice. NMuMG-encapsulated (○), NMuMG/VEGF-encapsulated (●), and NMuMG/sNRP-1–encapsulated (▴) cells (5 × 105 cells per mouse) were injected at the site of M1 cell injection, 72 hours later. The mice (10 per group) were followed for tumor volumes at the indicated times. (B) Final tumor weights. Tumors were harvested 21 days after M1 cell injection and weighed. The average weight and standard deviations were calculated for NMuMG (control), NMuMG/VEGF (VEGF), and NMuMG/sNRP-1 (sNRP-1) groups.
