Fig. 1.
Fig. 1. Immunohistochemical detection of bFGF expression. / Immunohistochemical detection of bFGF expression in bone marrow biopsies from (A) polycythemia vera (PV), (B) prefibrotic stage of idiopathic myelofibrosis (IMF), (C) chronic myeloid leukemia (CML), and (D) reactive changes. A strong nuclear labeling exceeding that of all other bone marrow cells can be observed in PV and IMF (A,B). A considerably weaker and faint staining not highlighting the megakaryocyte nuclei occurred in CML and reactive controls (C,D). Magnification (A,B), × 400; (C), × 200; and (D), × 300 (polyclonal antibody #AF-233-NA, R&D Systems, Minneapolis, MN, diluted 1:50).

Immunohistochemical detection of bFGF expression.

Immunohistochemical detection of bFGF expression in bone marrow biopsies from (A) polycythemia vera (PV), (B) prefibrotic stage of idiopathic myelofibrosis (IMF), (C) chronic myeloid leukemia (CML), and (D) reactive changes. A strong nuclear labeling exceeding that of all other bone marrow cells can be observed in PV and IMF (A,B). A considerably weaker and faint staining not highlighting the megakaryocyte nuclei occurred in CML and reactive controls (C,D). Magnification (A,B), × 400; (C), × 200; and (D), × 300 (polyclonal antibody #AF-233-NA, R&D Systems, Minneapolis, MN, diluted 1:50).

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