Fig. 1.
The TC Pro259Arg polymorphism is a C-to-G substitution at nucleotide 776.
(Top) Sequence analysis of the TC gene in one individual homozygous for the wild-type 776CC genotype that encodes proline at codon 259. (Bottom) Sequence analysis of the TC gene in one individual homozygous for the 776GG genotype that encodes arginine at codon 259.