Fig. 4.
VLA-4– and VLA-5–dependent transmigration of synchronized CD34+ cells.
Migration of CD34+ cells across Fn toward MS-5 CM was determined at indicated stages of the cell cycle after neutralization of α4 or α5 integrin (n = 3). Percent inhibition was determined relative to CD34+ cells incubated with control mouse IgG. Migration inhibition by indicated blocking antibody was significantly different from that observed in freshly isolated G0/G1 cells (*P < .05).