Adhesion of synchronized LTC-ICs on Fn.

(A) Adhesion of LTC-ICs was determined on Fn- or BSA-coated plates at indicated stages of the cell cycle (n = 4). Adhesion on Fn was statistically different between indicated stages (*P < .05). (B) LTC-IC adhesion to Fn was determined after blocking α4 or α5 integrin (n = 4). Binding inhibition was expressed relative to LTC-ICs incubated with mouse IgG. *Binding inhibition by indicated antibody was significantly different from that observed in freshly isolated LTC-ICs (P < .05).