Fig. 1.
![Fig. 1. Effects of kallistatin on VEGF- and bFGF-induced proliferation, migration, and adhesion of HMVECs. / (A,B) Quiescent HMVECs were incubated with the indicated concentrations of human kallistatin (HKBP) and VEGF or bFGF (15 ng/mL) for 24 hours. DNA synthesis was measured as [3H]-thymidine incorporation. Each value represents mean ± SEM (n = 4). (C) Cell migration was determined using modified Boyden chambers. VEGF or bFGF, 15ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 3). (D) Cell adhesion was determined using fibronectin-coated plates. VEGF or bFGF, 15 ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 4).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/100/9/10.1182_blood-2002-01-0185/4/h82123311001.jpeg?Expires=1735537688&Signature=eHcY8U1Uf-INCo5X-n3~QEp7QgJzHngBfOTY2UTvSx9eEvXL9~mrgQTIitgXPBz-BIUIgaiaCt5sf0qzw90x9Oi2pEmjg-ZPh~gvCCQ37tVudgql6LMDQ5d8p60lTB0bl9KO99Fl8l-00Q~30xqhiOosOXsOmuq8lptdoyCGXQ-tVmyD3hTxvyThCavd4QrDTqsKo2c2Zt1dgTmtnsJJQSeKYDvdEYlud~ukW-2-g4MrUc71KkBYu1UuJg9xVRzLNdZr18nYE1UdHU~bjOYdjLF81~hgw6ZSJLFIVp9CbbKYpzgNkzpqGNeHL0cSzaJ3r~jBfFo3IJj9c0hpIBBGaw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of kallistatin on VEGF- and bFGF-induced proliferation, migration, and adhesion of HMVECs.
(A,B) Quiescent HMVECs were incubated with the indicated concentrations of human kallistatin (HKBP) and VEGF or bFGF (15 ng/mL) for 24 hours. DNA synthesis was measured as [3H]-thymidine incorporation. Each value represents mean ± SEM (n = 4). (C) Cell migration was determined using modified Boyden chambers. VEGF or bFGF, 15ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 3). (D) Cell adhesion was determined using fibronectin-coated plates. VEGF or bFGF, 15 ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 4).
