Fig. 3.
Decreased IFN-α production correlates with low numbers of CD123+ dendritic cells in the circulation.
PBMCs from healthy donors, mycosis fungoides patients, and SzS patients with different levels of tumor burden were stimulated with 14 HAU of influenza virus A/Puerto Rico/8/34 (PR8) or allantoic fluid (data not shown) for 48 hours. Cytokine levels were measured in cell-free supernatants by ELISA. Data represent means (±SD) of tested patients. *P < .001; **P < .01, compared with healthy donors.