rCD40L induces activation of dendritic cells and monocytes as evidenced by up-regulation of CD80 molecules.

Blood from a healthy donor (A) and patient with low tumor burden (B) was stimulated with medium or rCD40L for 8 hours and then stained, and lineage-negative cells were analyzed for the coexpression of HLA-DR/CD11c and CD80 or CD14 and CD80. Right upper quadrant numbers represent the percentages of double-positive cells.