Effect of depletion of Ly49G2⁺ or Ly49C/I⁺ NK subsets in H2^b C57BL/6 mice on the engraftment of H2^d allografts.

Mice were given various mAb treatments or NRS 2 days before irradiation. Irradiated mice (4 mice/group) received 0.5 × 10⁶ (A) or 25 × 10⁶ (B,C) allogeneic BMCs. On the eighth day a soft agar colony assay was done to assess hematopoietic progenitor content in the spleens (mean ± SD). *Values significantly (P < .0001) greater than mice receiving NRS in experiment A; **values significantly (P < .0001) greater than mice receiving NRS in experiment A; ***values significantly (P < .006) lower than mice receiving NRS in experiment B; ****values significantly (P < .003) lower than mice receiving NRS in experiment C; *****values significantly (P < .001) greater than mice receiving anti-Ly49G2 (mAb 4D11) only in experiment C.