Fig. 7.
hGM-CSF mediated changes in expression of differentiation markers of cells expressing mutant hGM-CSF receptors.
Cells expressing (A) hGM (M) Rα, hβc and (B) hGM/βc, hβc cells were cultured in 1 ng/mL hGM-CSF for 7 days. The levels of expression of the differentiation markers are shown as representative histograms from at least 3 experiments (____). Nonspecific labeling was determined using the corresponding isotype control (- - -). The results obtained for cells cultured in murine cytokines that promote G/M Diff for 7 days are also shown for comparison.