hGM-CSF mediated changes in expression of differentiation markers of cells expressing mutant hGM-CSF receptors.

Cells expressing (A) hGM (M) Rα, hβ_c and (B) hGM/β_c, hβ_c cells were cultured in 1 ng/mL hGM-CSF for 60 days. The levels of expression of the differentiation markers are shown as representative histograms from at least 3 experiments (^____). Nonspecific labeling was determined using the corresponding isotype control (- - -). The results obtained for cells cultured in murine cytokines that promote G/M Diff for 7 days after 60 days culture in hGM-CSF are also shown.