Fig. 3.
Absolute number of peripheral blood monocytes and their CD64 expression during the first course.
CD64 expression on CD14+ cells was determined by FACS analysis and correlated to an isotype control (CD64 index = CD64 mean fluorescence intensity/mean fluorescence intensity isotype control) and measured immediately before and 4 hours after the end of infusion of H22xKi-4. Values are the means of the 6 patients treated with 20 mg/m2/d. There was a decrease of the CD64 expression on peripheral blood monocytes (day 1 P = .025; day 3 P = .095; day 5 P = .033; day 7P = .118). Error bars represent the SD.