JAQ2 and JAQ3 do not inhibit platelet aggregation induced by CRP and collagen.

(A-B) Heparinized prp was stimulated with CRP (A) or collagen (B) and aggregation was recorded. The results shown are representative of 6 individual experiments. (C-D) Heparinized prp was incubated with different concentrations of IgG2a (○), JAQ1 (▿), JAQ2 (■), or JAQ3 (⋄) for 5 minutes before the addition of CRP (0.25 μg/mL, C) or collagen (5 μg/mL, D) and aggregation was recorded. Results are expressed as mean ± SD of 6 mice/group.