HO-1 expression in the aortas of adult (20-week-old) and young (8-week-old) SHRs and WKYs.

Representative Western immunoblotting (A) and the mean relative abundant levels of expressed proteins (B) revealed a significantly increased expression of HO-1 protein in the aortas from young SHRs that received hemin treatment. The basal HO-1 expression level from adult SHRs was significantly greater than in the age-matched WKYs, which were not affected by hemin. †P < .01 versus age-matched WKYs. *P < .05 versus all other groups. ΔP < .05 versus age-matched animals of same species without hemin treatment. The ages of the animals in weeks are indicated as “20” and “8” in (A) and (B). n = 4 for each group. Error bars indicate means ± SEM.