Cytolytic activity of P1218-specific CTLs against cell line targets.

(A) Cytotoxicity against cell lines that do or do not express HLA-A0201 and CD45. The figure shows the means ± SDs of 3 experiments performed in duplicate or triplicate. (B) Cytotoxicity against the HLA-A0201⁺, CD45⁺ cell line C1R-A2 in the presence of a 20-fold excess of cold T2 targets loaded with either P1218 or the control peptide HBV (18-27). Mean cytotoxicity ± SD is shown in a representative experiment performed in triplicate.