Normal growth of CFU-M/GM colonies despite overexpression of RPS19.

CD34⁺ cells from DBA patients 1-4 (2 experiments each, n = 8) and healthy individuals (n = 4) were transduced with the MRIG and MGIN vectors, sorted for GFP⁺ cells, and plated in methylcellulose. On day 14, the number of CFU-M and CFU-GM colonies was evaluated. The CFU-M and CFU-GM colony data were pooled together and are shown as CFU-M/GM colonies. The bar graphs show the mean ± SEM. No significant difference in colony formation was detected between the MRIG-transduced and the control vector–transduced cells.