Fig. 1.
Fig. 1. Expression of Skp2 and p27Kip1 in PBLs and cell lines derived from hematopoietic neoplasms. / Quiescent PBLs express high levels of p27Kip1 that decrease upon activation with phytohemagglutinin (PHA). Levels of Skp2 protein expression show an inverse relationship to levels of p27Kip1 in 10 of 15 cell lines. Quiescent PBLs and their activated counterparts show the absence of Skp2 protein expression.

Expression of Skp2 and p27Kip1 in PBLs and cell lines derived from hematopoietic neoplasms.

Quiescent PBLs express high levels of p27Kip1 that decrease upon activation with phytohemagglutinin (PHA). Levels of Skp2 protein expression show an inverse relationship to levels of p27Kip1 in 10 of 15 cell lines. Quiescent PBLs and their activated counterparts show the absence of Skp2 protein expression.

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