Fig. 4.
Fig. 4. CXCR5 expression in tonsil and PCNSL. / (A) Immunohistochemical examination of brain biopsy specimen from a patient with PCNSL demonstrates expression of CXCR5 by cells of perivascular malignant infiltrates (BCIP/NBT, no counterstain, original magnification × 400). (B) Normal tonsil shows CXCR5-expressing cells in lymphoid follicles, particularly in the mantle zone (BCIP/NBT, no counterstain, original magnification × 400).

CXCR5 expression in tonsil and PCNSL.

(A) Immunohistochemical examination of brain biopsy specimen from a patient with PCNSL demonstrates expression of CXCR5 by cells of perivascular malignant infiltrates (BCIP/NBT, no counterstain, original magnification × 400). (B) Normal tonsil shows CXCR5-expressing cells in lymphoid follicles, particularly in the mantle zone (BCIP/NBT, no counterstain, original magnification × 400).

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