Fig. 2.
Fig. 2. Murine spleen engraftment by human CD34+subsets is mediated by CXCR4. / Dose dependent inhibition of spleen repopulation by anti-CXCR4 mAb. The levels of human cell engraftment in the spleen of mice presented in Figure 1, panels C and D, were summarized. ■ represents transplantation of cells without additional mAb; ░ indicates coinjection with anti-CXCR4 mAb (10 μg/mouse) and ▪ represents 50 μg/mouse or background levels determined by staining with isotype control mAb, as indicated. Transplanted subsets and P values are indicated.

Murine spleen engraftment by human CD34+subsets is mediated by CXCR4.

Dose dependent inhibition of spleen repopulation by anti-CXCR4 mAb. The levels of human cell engraftment in the spleen of mice presented in Figure 1, panels C and D, were summarized. ■ represents transplantation of cells without additional mAb; ░ indicates coinjection with anti-CXCR4 mAb (10 μg/mouse) and ▪ represents 50 μg/mouse or background levels determined by staining with isotype control mAb, as indicated. Transplanted subsets and P values are indicated.

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