Fig. 7.
SAHA suppresses the stimulation of production of IL-6 by BMSCs triggered by binding of MM cells.
MM.1S cells were cocultured with or without BMSCs for 24 hours, in the presence or absence of SAHA (5-10 μM). During this incubation period, the viability of BMSCs was maintained. The presence of IL-6 in the supernatants was quantified by ELISA. Error bars represent SD.