Differences in cellular resistance to cytarabine (Ara-C), daunorubicin (DNR), and etoposide (VP16), comparing samples with abnormalities in chromosome 5/7 versus all other de novo childhood AML cases.

Results are expressed as LC₅₀ values (μg/mL). Dots represent the median LC₅₀ values, the triangles the 25th and 75th percentiles. Cases with chromosome 5/7 abnormalities (n = 8) were significantly more resistant to cytarabine (median 3.9-fold) but not to etoposide and daunorubicin when compared with the other AML samples (n = 101) without chromosome 5/7 abnormalities.