Fig. 2.
Differences in cellular resistance to cytarabine (Ara-C), daunorubicin (DNR), and etoposide (VP16) when the subgroup of childhood AML samples with t(9;11) was compared with all other de novo childhood AML cases.
Results are expressed as LC50 values (μg/mL). Dots represent the median LC50 values, the triangles the 25th and 75th percentiles. Samples with t(9;11) (n = 9) were significantly more sensitive to cytarabine (Ara-C, median 2.9-fold), daunorubicin (DNR, 2.9-fold), and etoposide (VP16, 13.1-fold) than the complementary group of AML samples (n = 100).