Fig. 7.
Inhibition of caspase activity and Bcl-XLcleavage.
WSU-CLL and ALL-REH were exposed to 500 nM CD437 in the presence or absence of the pan-caspase inhibitor zVAD-fmk (200 nM). Cells were harvested 24 hours later, and Bcl-XL cleavage was assessed by Western blot. Actin was used as loading control.