Fig. 3.
Fig. 3. Concentration-response curves. / Curves of (A) ADP- or (B) 2-MeSADP–induced inhibition of adenylyl cyclase stimulated with 20 μM forskolin in CHO-K1 cells stably expressing either P2Y12WT, P2Y12Cys17Ser, P2Y12Cys270Ser, or P2Y12Cys17Ser/Cys270Ser. Data were normalized to the maximal response obtained in the absence of ADP or 2-MeSADP (mean ± SE, n = 3-7).

Concentration-response curves.

Curves of (A) ADP- or (B) 2-MeSADP–induced inhibition of adenylyl cyclase stimulated with 20 μM forskolin in CHO-K1 cells stably expressing either P2Y12WT, P2Y12Cys17Ser, P2Y12Cys270Ser, or P2Y12Cys17Ser/Cys270Ser. Data were normalized to the maximal response obtained in the absence of ADP or 2-MeSADP (mean ± SE, n = 3-7).

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