Effects of desmopressin on von Willebrand factor antigen levels (VWF:Ag), VWF cleaving-protease activity (ADAMTS13), VWF propeptide (VWF:pp), VWF collagen-binding (VWF:CBA), and VWF multimer pattern (VWF:MM) in 3 patients with type 1 von Willebrand disease.

All patients received DDAVP (0.3 μg/kg) over 30 minutes intravenously. Symbols show data of all 3 patients with von Willebrand disease: patient 1, ●; patient 2, ▪; patient 3, ▴. Presence of unusually large (UL) VWF:MM is indicated by +; absence of UL VWF:MM, −.