IHC and ISH patterns.

Samples with positive and negative (or high vs low expression) for each marker are shown. All these cases are representative of classical HL, with either nodular sclerosis or mixed cellularity. Original magnification for cyclins, MIB1, Rb, p53, p27, p65/RelA, Bcl6, TUNEL, and EBER, × 1000; remaining panels, × 600.