Fig. 2.
Gain of P2X1 functionality in TG platelets.
(A) Increased P2X1-mediated Ca2+ influx in TG platelets. (B) Enhanced P2X1-mediated TG platelet shape change. Apyrase (2 U/mL)–treated washed platelets were stimulated with αβ-meATP (1 μM) in the presence of 2 mM CaCl2. Data are representative curves of at least 2 separate experiments performed in triplicate on platelet pools from 3 animals. Arrows indicate the addition of αβ-meATP (1 μM).
