Fig. 7.
Effects of protein synthesis inhibitors (act-D and Chx), monensin, PP1, and U73122 on DEX-induced caspase 8 activation.
Thymocytes were treated for different times with DEX (10−7M; A) or were pretreated for 30 minutes with 2.5 μg/mL act-D (B), 50 μg/mL Chx (C), 2.5 μM U73122 (D), 10 μg/mL monensin (E), or 10 μM PP1 (F) before DEX treatment. Caspase-8 cleavage was evaluated by Western blot analysis with anti–caspase-8 antibody.
