Multimer patterns of plasma VWF in VWD patients.

SDS–1.5% agarose gel electrophoresis was performed in all VWD patients studied in this work. Three type 2A VWD patients completely lack the larger and intermediate VWF multimers in plasma. Compared with type 2A patients, the lack of larger VWF multimers in all type 2B patients was less severe, with intermediate forms retained.