Fig. 1.
CD4 T-cell counts
. (A) Counts of circulating CD4 T cells and CD4 T-cell subsets (left) and their increases relative to week 6 (right) in IL-7–treated animals (filled symbols) and placebo-treated animals (open symbols), showing that CD4 T-cell counts increased more in IL-7–treated than placebo-treated animals and that this was primarily, if not entirely, due to peripheral expansion. The animals were treated with IL-7 or placebo between 6 and 10 weeks after transplantation, as indicated in each graph by the horizontal black bar. “Norm” shows the counts determined in normal animals of similar age as the animals that received transplants. (B) Percent TREC-containing CD4 T cells among total CD4 T cells in IL-7–treated animals (filled symbols) and placebo-treated animals (open symbols). For other symbols, refer to panel A.