Percentages of annexin V⁺ or 7-AAD⁺ cells.

Percentages of dying/dead (annexin V⁺) as well as dead (7-AAD⁺) CD4 T cells were not decreased in IL-7–treated (filled symbols) compared to placebo-treated (open symbols) animals. This applied to both blood (left panels) and axillary LNs (right panels). Percentages of annexin V⁺ or 7-AAD⁺ cells among total CD4 T cells are shown. “Norm” denotes the percentages determined in normal animals of similar age as the animals receiving transplants. In one placebo-treated animal, LN sampling at 5 to 6 months after transplantation was not done. Both in IL-7– and placebo-treated animals, the percentage of dying or dead CD4 T cells was always greater in LNs than in blood. The animals were treated with IL-7 or placebo between 6 and 10 weeks after transplantation as indicated by the horizontal black bars.