Clonality assay of patient 4.

Clonality assay using glucose-6-phosphate dehydrogenase (G6PD) polymorphism (1311C>T). Control: Granulocyte RNA from a homozygous T (T), a homozygous C (C), and a heterozygous T/C (T/C) healthy control were used as a source of cDNA used for SSCP analyses. Patient 4: Expression of both C and T alleles was observed in platelet (PLT) and granulocyte RNA (GNC), indicative of a polyclonal hematopoiesis. Similar results were obtained in patients 1, 6, and 7 (data not shown).