Fig. 1.
![Fig. 1. Effect of ciprofibrate and Wy 14643 on CRP and fibrinogen expression in human hepatocytes stimulated by IL-1 and IL-6. / CRP (A) and fibrinogen (B) concentrations were measured in culture medium by ELISA and were expressed as means ± SDs. Human hepatocytes were isolated and treated for 16 hours with 250 μM ciprofibrate (CF), 250 μM Wy 14643 (WY), or vehicle (dimethyl sulfoxide [DMSO]; C) and subsequently were stimulated with 25 ng/mL IL-1 or IL-6 for an additional 24 hours. Results of 1 representative experiment of 3 experiments with different donors are shown. *P < .05 compared with control.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/2/10.1182_blood-2002-06-1762/4/h80233682001.jpeg?Expires=1735508901&Signature=rOHJK8tLNIGE7eUBLcDs~MD1FaCPhIaIfu~6rDS~RubHkqOuVaJQsTenMHqcey-gQ0GYNXd2gOgF4Vs5~c7uey9RRfGpDYyQLVFu7dD29SIUWaDghXaiqbJQu7peWKLnar1iy-0N~J7luXrsF-XFmB0ALrEmbuCWVZY4RpB63ac0WFdLxAkr4yX2rr1i~vqEP5vstr7aHewZoxwc0lCbN7nxMnut4DLh0ubfUV0m7NoEFYbD8TSY9CL5euuCXuqEquvltzF7vVLiJJSi3KCtGUj~YiSNnLJfW3ZG~2VUcxQDCvJ4UD6UgBukWBg0Ekn6mhBItM8kCaU15YX4N7onQg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of ciprofibrate and Wy 14643 on CRP and fibrinogen expression in human hepatocytes stimulated by IL-1 and IL-6.
CRP (A) and fibrinogen (B) concentrations were measured in culture medium by ELISA and were expressed as means ± SDs. Human hepatocytes were isolated and treated for 16 hours with 250 μM ciprofibrate (CF), 250 μM Wy 14643 (WY), or vehicle (dimethyl sulfoxide [DMSO]; C) and subsequently were stimulated with 25 ng/mL IL-1 or IL-6 for an additional 24 hours. Results of 1 representative experiment of 3 experiments with different donors are shown. *P < .05 compared with control.
