Purified

M luteus peptidoglycan produces larger and more inflamed lesions in lys M^−/− mice. Each panel is a photograph of a lesion in an individual mouse on day 2. (A) F2 controls; (B) lys M^−/− mice. (C) Areas of lesions in lys M^−/− mice (▿) compared with F2 controls (●). Note that lesion areas are significantly larger in lys M^−/− mice than in F2 controls (P < .001).