Effect of the Cb2-specific antagonist SR144528 on G-CSF–induced differentiation.

(A) Cb2-specific antagonist titration experiment when added to the G-CSF cultures in differentiation assays. Countings were carried out at day 9 of culture. (B) Effect of Cb1-specific (C1) and Cb2-specific (C2) antagonist (100 nM) on 2 Cb2-EGFP and 2 EGFP clones cultured for 9 days in the presence of G-CSF (G). White represents blast cells, black represents intermediate forms, and gray indicates neutrophils.