Adenosine inhibits and increases DC release of CXCL10 and CCL17, respectively.

DCs were stimulated (●) or not (○) with 3 μg/mL LPS in the absence or the presence of adenosine. Supernatants were harvested after 24 hours and CXCL10 (A) and CCL17 (B) were measured by ELISA. Results are expressed as mean ng/mL ± SD of triplicate cultures.P < .02 between LPS- and LPS + adenosine–treated DCs at all the concentrations of adenosine tested. Shown is 1 of 4 experiments performed.