Clonogenic survival assay of fibroblasts after ionizing radiation.

Fibroblasts from 5 T⁻B⁻NK⁺ SCID patients from 4 families without RAG mutations were radiosensitive. Data from the 4 patients with Artemis gene mutations are shown. NBS indicates Nijmegen breakage syndrome. Each survival curve represents the mean of at least 3 independent experiments. Error bars represent standard errors of the mean.