Fig. 3.
Binding of ΔLNGFR on the surface of LV'VFas+ cells by the LNGFR+ microbeads does not induce signaling of the intracellular Fas domains and cell death.
Macaque T cells were transduced with either the LV'VFas or the LV'V retroviral vector and on day 6 enriched for ΔLNGFR expression. Aliquots of cells were then evaluated for growth. LV'V-modified: unselected (▵), positive fraction (■), depleted fraction (⋄); LV'VFas-modified: unselected (▴), positive fraction (▪), depleted fraction (♦). The arrow indicates the day of the ΔLNGFR selection. Data shown are from 1 of 2 separate experiments.