Fig. 1.
Detection of P2Y1 in unstimulated platelets by immunogold labeling of frozen ultrathin sections using a MoAb directed against the amino-terminal domain.
(A) A typical distribution of the labeling within the different membrane systems of the platelet. Surface labeling is highlighted (arrows). (B-D) Higher-power magnification of labeled intracellular structures: thin channels of the OCS (arrowheads; B), a more dilated element of the OCS (C), and the delimiting membranes of α-granules (arrow) (D). The presence of multivesicular bodies (MVBs) inside the granule is indicated. Bars = 0.1 μm.
