Fig. 1.
Immunodeficient (NOD/SCID) mouse liver damaged by CCl4, with and without rescue by hepatocyte growth factor (HGF).
Human stem cell–engrafted mice were injected intraperitoneally with 0.4 mL/kg carbon tetrachloride (CCl4), and then treated with or without 4 intraperitoneal injections of 1.5 μg recombinant human HGF (rhHGF) at 12-hour intervals, 48-72 hours after CCl4 treatment. (A) Age-matched normal liver. (B) CCl4-treated liver. (C) Mouse liver treated with CCl4 and HGF.
