Fig. 9.
Fig. 9. Intact barrier response against MHC-mismatched progenitors in the absence of 3 cytotoxic pathways. / B6-cdd recipients were primed against H-2d by injection of BALB/c cells 3 weeks prior to BM transplantation. Naive BALB/c recipient controls were used to demonstrate the upper limit (100%) of lineage-committed progenitors in the CFU-IL3 assay for each of the donor marrow inocula. Naive BALB/c recipients of 5 × 106TCD–wild-type BM contained 98 ± 25 CFU-IL3/spleen and 414 ± 124 CFU-IL3/spleen from TCD-TNFR1−/− BM.

Intact barrier response against MHC-mismatched progenitors in the absence of 3 cytotoxic pathways.

B6-cdd recipients were primed against H-2d by injection of BALB/c cells 3 weeks prior to BM transplantation. Naive BALB/c recipient controls were used to demonstrate the upper limit (100%) of lineage-committed progenitors in the CFU-IL3 assay for each of the donor marrow inocula. Naive BALB/c recipients of 5 × 106TCD–wild-type BM contained 98 ± 25 CFU-IL3/spleen and 414 ± 124 CFU-IL3/spleen from TCD-TNFR1−/− BM.

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