IL-7–displaying HIV-1–derived vectors promote T-cell survival.

The forward/side scatter profiles of adult memory (CD45RO), adult naive (CD45RA), and cord blood–naive (CD45RA) CD4⁺ T cells that were incubated for 12 days with VSV-G–pseudotyped vectors (G), IL-7–displaying lentiviral vectors (G/IL7SU), or VSV-G–pseudotyped lentiviral vectors in the presence of rIL-7 (15 ng/mL; G+rIL-7) are shown. The percentage of viable cells, in the R1 gate, is indicated in each dot blot. Viability of all freshly isolated cells was higher than 98% (not shown).